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Gatifloxacin hydrochloride

CAS No. 121577-32-0

Gatifloxacin hydrochloride ( AM 1155 hydrochloride;BMS 206584-01 hydrochloride;PD 135432 hydrochloride )

Catalog No. M10807 CAS No. 121577-32-0

A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Gatifloxacin hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV.
  • Description
    A fourth-generation fluoroquinolone antibiotic that inhibits the bacterial DNA gyrase and topoisomerase IV; displays 2- to 16-fold more active than ciprofloxacin and ofloxacin against Staphylococcus aureus with MICs of 0.1-0.78 ug/mL.
  • Synonyms
    AM 1155 hydrochloride;BMS 206584-01 hydrochloride;PD 135432 hydrochloride
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    121577-32-0
  • Formula Weight
    411.86
  • Molecular Formula
    C19H23ClFN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F.Cl
  • Chemical Name
    3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-, hydrochloride (1:1)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hosaka M, et al. Antimicrob Agents Chemother. 1992 Oct;36(10):2108-17.
2. Tomioka H, et al. Antimicrob Agents Chemother. 1993 Jun;37(6):1259-63.
3. Wakabayashi E, et al. Antimicrob Agents Chemother. 1994 Mar;38(3):594-601.
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